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Joshua K. Craver, Chad T. Miller, Kimberly A. Williams and Nora M. Bello

-Laboratory Corporation, Westlake, OH); 3) UVB-blocked: the same as treatment UVB with the addition of Mylar ® sleeves (North Solar Screen, Andover, MA) placed over the lamps to block UVB light; and 4) full-spectrum: control lighting using full spectrum lamps, as

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Peter M.A. Toivonen, Jared Stoochnoff, Kevin Usher, Changwen Lu, Paul A. Wiersma and Chunhua Zhou

on ultraviolet reflectance and consequent association with red blush development on the apple. The mechanism by which plants detect UVB light has recently been shown to involve the UVR8 receptor in cooperation with COP1 and HY5 ( Singh et al., 2014

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Shiow Wang, Ren-tian Feng, Linda Bowman, Ross Penhallegon and Min Ding

The effects of lingonberry (Vaccinium vitis-idaea L.) extracts on activator protein-1 (AP-1), nuclear factor-kappaB (NF-κB), and mitogen-activated protein kinases (MAPKs) were evaluated. Pretreatment of JB6 P+ mouse epidermal cells with lingonberry extracts produced a dose-dependent inhibition of AP-1 and NF-κB induced by either 12-O-tetradecanoylphorbol-13-acetate (TPA) or ultraviolet-B (UVB) light. Lingonberry extracts blocked UVB-induced phosphorylation of MAPK family members ERK1, ERK2, and p38, but not JNK. Lingonberry extracts also prevented TPA-induced phosphorylation of ERK1 and ERK2. Results of soft agar assays indicated that lingonberry extracts suppressed TPA-induced neoplastic transformation of JB6 P+

cells in a dose-dependent manner. Lingonberry extracts also induced the apoptosis of human leukemia HL-60 cells in a dose-independent manner. These results suggest that ERK1 and ERK2 may be inhibited by lingonberries, which results in suppression of AP-1 and neoplastic transformation in JB6 P+ cells and causes cancer cell death by an apoptotic mechanism in human leukemia HL-60 cells.

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Yi Gong, Ronald B. Pegg, Adrian L. Kerrihard, Brad E. Lewis and Richard J. Heerema

fused-core HPLC columns and their characterization J. Agr. Food Chem. 65 5810 5820 Hall, G.D. 2000 Pecan food potential in prehistoric North America Econ. Bot. 54 103 112 Heck, D.E. Vetrano, A.M. Mariano, T.M. Laskin, J.D. 2003 UVB light stimulates