A 2-year field study was conducted in two locations in the Dominican Republic to determine the influence of various support systems and nitrogen fertilization programs on passion fruit (Passiflora edulis var. flavicarpa) yield and economic returns. Three trellis systems were used: 1) single line, where a single wire was placed along the planting rows at 2 m high; 2) double lines, where two wires were established along the planting rows at 2 and 1 m high, respectively; and 3) crossed lines, with wires at 2 m high, allowing the vines to grow both along and across the planting rows. Nitrogen (N) fertilization rates were 13, 26, and 52 g/plant of N every 20 days. Plants trained with the single- and double-line support systems combined with 52 g/plant of N had higher marketable yield and had the lowest proportion of non-marketable fruit/plant per year. Partial budget analysis indicated that the single-line support system had a marginal return rate of 36% compared to the double-line support system.