A number of pre-emergence soil residual herbicides were tested at 2 locations on varieties of young peach, plum, cherry, pear and walnut rootstocks. The greatest variation in response resulted from differences in location. Important differences in varietal response were also obtained with the various herbicides in light soils. Simazine appeared sufficiently safe to trees in heavier soil but gave variable weed control. Diuron gave about the same degree of weed control but more safety than simazine on young trees. Of the uracil herbicides tested, DP-733 was the least toxic to the fruit tree species tested, while bromacil and isocil were generally the most toxic, except to peach trees. Of the commercial uracil herbicides, only DP-732 (terbacil) was of sufficient interest for further study.