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Four sweetpotato breeding lines were tested for their sodium tolerance in sand culture. All plants were grown in the greenhouse in sterilized sand and watered daily with a modified half-Hoagland solution (N: K-1:2:4). Four sodium levels (0, 35, 70, and 105 ppm) were applied to the breeding lines in a split-plot design with four replications. Soil leachate was collected every 2 days and was measured for P, Na concentration, and electrical conductivity. Plants were grown for 60 days. Preliminary results from analysis of soil leachate showed an increase in EC as sodium concentration increased 5 days after treatments were initiated. Potassium and Na concentration varied with each breeding line tested. Storage root fresh and dry weight were significantly affected by Na levels (i.e., lines tested were tolerant ≤70 ppm Na).