Large natural genetic diversifications have occurred among Chinese tree peony cultivars under the natural and artificial selections on the flower for ornamental and medicinal uses in the past over 1500 years in China. Paeonia suffruticosa ‘Zi Mei You Chun’ X.Q. Zhao & J.P. Zhao & X.Z. Zhao & X.C. Zhao & Q.X. Gao & Z.Q. Zhao & J.X. Zhao & Z.L. Suo (Paeoniaceae) is a unique cultivar possessing side flowers and bicolored floral disc belonging to the Central Plains tree peony cultivar group of China. This natural mutant is not only an outstanding ornamental, but also a valuable material for scientific research on evolution of tree peony cultivars, metabolic pathways of pigments in the floral disc, origin of floral disc in Paeoniaceae, and other issues in plant evolutionary and developmental genetics.