Pesticides and alternative fruit thinners are needed for certified organic fruit growers. Transient reductions in photosynthesis (Pn) have proven an effective technique for fruit thinning. Pesticides can be detrimental to plant growth by Pn reduction. A two-part study was developed to measure plant response to foliar applications of sulfur compounds. In study 1, 2% concentrations of various sulfur compounds were observed for potential physiological or pesticidal effects. Foliar treatments were applied to vegetative apple trees grown under controlled environment conditions to study photosynthetic effects. No treatments significantly reduced CO2 assimilation (A) and stomatal conductance (gs). Copper sulfate, ammonium sulfate, and potassium sulfate significantly reduced evapotranspiration (Et) 7 days after treatment. No significance was observed for plant growth. In study 2, a 2% potassium sulfate concentration significantly reduced A 22 days after treatment; however, no differences were observed for Et and gs. Differences in plant growth were not significantly different among treatments.