Field studies were conducted to determine the potential economic impact of the loss of pronamide herbicide to artichoke (Cynara scolymus L.) growers, and to evaluate pendimethalin as an alternative herbicide during establishment of artichoke. Two rates of pronamide and one rate of pendimethalin were applied to perennial and annual artichokes. With the exception of wild oat (Avena fatua L.), pendimethalin controlled weeds as well as or better than pronamide. Financial analysis of treatment effects was based on weed management expenses and value of yield. The financial effect of using pronamide in perennial artichoke ranged from a loss of $247 to a gain of $326 per ha, whereas its use in annual artichoke increased revenue $542 to $5499 per ha. The effects on revenue of using pendimethalin varied with weed species composition and density. For three sites, revenue increased from $267 to $5056 per ha, while a loss of $1034 per ha occurred at a site with a heavy infestation of wild oat. We conclude that pendimethalin has potential as a pronamide replacement, or as a complement to pronamide. Chemical names used: 3,5-dichloro (N-1,1-dimethyl-2-propynyl)benzamide (pronamide); N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzenamine (pendimethalin).