Several chemicals applied to dry seeds by means of organic solvents were successful in preserving seed quality as determined by germinating capability of seeds or ATP content. The fungicide (pentachloronitrobenzene)-treated, injured or healthy pea (Pisum sativum L. cv. Alaska) seeds were highly resistant to infection by Aspergillus ruber (Konig, Spiekerman and Bremer) Thom and Church (NRRL 52), a storage fungus. The insecticide, Chlorpyrifos caused the lima bean (Phaseolus lunatus L. cv. Fordhook 242) seeds to produce seedlings with reduced levels of damage from the seed-corn maggot, Hylemya platura (Meigen). The antibiotics, chloramphenicol and puromycin, slowed down the rate of deterioration of lettuce (Lactuca sativa L. cv. Grand Rapids) seeds stored under accelerated aging conditions [43°C & 85% Relative Humidity (RH)].