Vermicomposting is a promising method of transforming unwanted and virtually unlimited supplies of organic wastes into usable substrates. In this process, the digestive tracts of certain earthworm species (e.g., Eisenia fetida) are used to stabilize organic wastes. The final product is an odorless peat-like substance, which has good structure, moisture-holding capacity, relatively large amounts of available nutrients, and microbial metabolites that may act as plant growth regulators. For these reasons, vermicompost has the potential to make a valuable contribution to soilless potting media. The objective of this study was to evaluate the transplant quality and field performance of vegetable transplants grown in vermicompost. Tomato (Lycopersicon esculentum Mill.), eggplant (Solanum melongena L.), and pepper (Capsicum annuum L.) transplants were grown in a commercial soilless mix including 0%, 10%, or 20% (v/v) worm-worked cattle manure. Growth of vegetable transplants was positively affected by addition of vermicompost, perhaps by altering the nutritional balance of the medium. Transplant quality was improved in peppers and eggplants while tomato transplant quality was slightly reduced. There were no significant differences in field performance.