Selection and propagation of rootstocks for apricot (Prunus armeniaca L.) varies worldwide in response to local climate, soils, and cultivars. In this paper we review published research focused on these local selective practices. Additionally, we review the current development of apricot rootstocks and suggest new research avenues to satisfy the needs of commercial apricot growers. Rootstocks are identified by their responses to biotic and environmental stresses, with specific adaptive characteristics that enable establishment and production under unique zonal ecologies. Desirable characteristics include scion compatibility, adaptation for heavy or wet soils, pest and disease resistance, ease of propagation, control of vegetative vigor, effects on dormant season physiology of the scion, precocity, fruit quality, and productivity. Interstocks that can overcome incompatible rootstock-scion combinations are covered. As worldwide consumer demand for apricots increases with improved apricot cultivars, rootstock selections and propagation must be developed for niche fruit with specific characteristics, intensive production systems, mechanized harvest, and marginal site selection.