Vigorous osteospermum (Osteospermum ecklonis) cultivars Congo and Wildside received foliar sprays of daminozide or daminozide + chlormequat (Expt. 1). Both cultivars responded similarly to the plant growth regulator (PGR) treatments. Only a limited amount of plant height control occurred using 5,000 mg·L-1 (ppm) daminozide + 1,500 mg·L-1 chlormequat or 5,000 mg·L-1 daminozide + 3,000 mg·L-1 chlormequat. Flowering was delayed, phytotoxicity was observed, while peduncle length increased, suggesting that higher concentrations of daminozide or chlormequat may or not be effective at any concentration and may result in increased phytotoxicity. In Expt. 2, `Lusaka' received foliar sprays or substrate drenches of paclobutrazol or uniconazole. Foliar sprays ≤80 mg·L-1 paclobutrazol or ≤24 mg·L-1 uniconazole were ineffective in controlling plant growth. Substrate drenches of paclobutrazol (a.i.) at 8 to 16 mg/pot (28,350 mg = 1.0 oz) produced compact plants, but at a cost of $0.23 and $0.46/pot, respectively, would not be economically feasible for wholesale producers to use. Uniconazole drenches were effective in producing compact `Lusaka' osteospermum plants. Uniconazole drench concentrations of 0.125 to 0.25 mg/pot were recommended for retail growers, while wholesale growers that desire more compact plants should apply a 0.25 to 0.5 mg/pot drench. Applying uniconazole would cost $0.06 for a 0.25 mg drench or $0.12 for a 0.5 mg drench.