Apple replant disease (ARD) is a common problem typified by stunted growth and reduced yields in successive plantings of apple (Malus ×domestica Borkh.) in old orchard sites. ARD is attributed to biotic and abiotic factors; it is highly variable by sites, making it difficult to diagnose and overcome. In this experiment, we tested several methods of controlling ARD in a site previously planted to apple for >80 years. Our objective was to evaluate practical methods for ARD management. We compared three different experimental factors: four preplant soil treatments (PPSTs) (compost amendments, fumigation with Telone C-17, compost plus fumigation, and untreated soil); two replanting positions (in the old tree rows vs. old grass lanes); and five clonal rootstocks (`M.26', `M.7', `G.16', `CG.6210', and `G.30') during 4 years after replanting. The PPSTs had little effect on tree growth or yields during 4 years. Tree growth was affected by planting position, with trees planted in old grass lanes performing better than those in the old tree rows. Rootstocks were the most important factor in overcoming ARD; trees on `CG.6210' and `CG.30' grew better and yielded more than those on other rootstocks. Rootstock selection and row repositioning were more beneficial than soil fumigation or compost amendments in controlling ARD at this orchard.