Chile pepper (Capsicum spp.) hybrids are normally produced by hand-emasculating the female parent and then pollinating the emasculated flower by hand. Increased yield has occurred with F1 hybrid seed, but the seed is considered too expensive by growers to be direct-seeded, a common production practice in the southwestern U.S. chile pepper industry. In ornamental flowers, when F2 hybrid seed is available, it is cheaper than F1 hybrid seed. If F2 hybrid chile pepper cultivars could manifest heterosis, and produce fruit quality acceptable to the chile pepper industry, then a less-costly alternative would be available to growers. A series of field trials with jalapeños was conducted to test F1 hybrid cultivars to their F2 progeny for yield and fruit quality. The results indicated that in some instances the F2 progeny can yield as well as the F1 hybrid parent. Therefore, F2 hybrid cultivars can be used in a commercial production system. However, if a male-sterility system is used to produce the F1 hybrid cultivar, the F2 progeny will have significantly lower yield than the F1 hybrid parent, as was the case in one accession in this trial. Nevertheless, F2 hybrid cultivars are an additional way to supply high yielding hybrid cultivars to growers.