Feverfew has aspirin-like properties and has been utilized for the treatment of pain, particularly migraine headache. Parthenolide is the sesquiterpene lactone believed to be responsible for the medicinal properties. The potential for utilizing existing tobacco production and handling systems for the production and postharvest handling of feverfew was investigated. In year one, 8 commercial tobacco growers each planted about one-half acre of feverfew (Tanacetum parthenium L. Schulz-Bip.). The yield of dry herb varied among farmers from about 122 to 772 (55 to 350 kg) pounds per half-acre. The parthenolide content of the dried herb from most producers was within the range desired by industry, but four factors precluded its salability: a) presence of foreign matter, primarily weeds; b) excessive ash content due to contamination from sandy soils; c) mold resulting from processing with excessive moisture content, and; d) insect infestation (tobacco beetles Lasioderma serricorne) during storage. All of these limitations resulted from the failure to implement good agricultural aractices (GAPs) and good manufacturing practices (GMPs) during production and handling of the product. A second planting of the feverfew was carried out with strict attention to GAPs and GMPs. In this trial, all of the dried feverfew met the requirements for sale. Here we report on the management of production and handling systems for feverfew that can enable growers to produce high quality herbs that meet the high standards for medicinal use.
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