This study was established to determine the influence of scion/stock combination on leaf area, yield efficiency, and fruit quality attributes in effort to identify the most suitable scion/stock combination for Mississippi. Twenty-nine scion/stock combinations were grown at the Pontotoc Ridge-Flatwoods Research and Extension Center, North Mississippi. The treatments were arranged in a completely randomized design (CRD) with six single tree replications. `Jon-A-Red' on Mark produced the smallest leaf area, while the largest leaf area was produced by the combination of `Royal Gala' on MM106 and `Blushing Golden' on M7A. Scion/stock combinations significantly affected yield efficiency, fruit yellow pigment dvelopment, firmness and fruit mineral composition. Scion cultivars on Mark resulted in the highest yield efficiency, except `Empire'. `Ultra Gold' and `Braeburn' on Mark and `Blushing Golden' on MM111 led to yellow pigmentation in the highest category. Meanwhile, `Braeburn' on Mark was among the scion/stock combinations that produced the firmest fruit. And fruit from trees on Mark consistently had high calcium (Ca) levels. After 7 years, `Royal Gala' on Mark produced the highest yield efficiency. `Braeburn' on Mark resulted in both the firmest fruit and the highest fruit Ca concentration.