Amelioration and/or reclamation of saline and non-saline soils is based on the application of high quantities of agrochemical products or high volumes of water, which causes an injury in soil or downward displacement of nutrients to the lower layers in soils. Research was conducted to evaluate the effect of application of citric industry waste on saline and non-saline soil. The waste has an electrical conductivity (EC) of 2.7 dS/m and pH of 3–4.2, 35% is organic material that is readily decomposed. This experiment was carried out on field conditions using applications of three different volumes, T1 = 3200, T2 = 6400, and T3 = 9600 m3·ha–1·m–1 and a control, no-waste, (T0), using just irrigation water (EC = 2.5 dS·m–1). The same treatments were added to non-saline soil. Effect of citric industry waste application in both saline and non-saline soils was similar. In all the treatments, EC was decreased with respect to T0 and soil before application (BA), the largest decrease was found in T3. pH decreased in the top soil layer much more than in the bottom layers. Ions were decreased in all soil profile. Organic matter (OM) was increased in the profile in treatment T1 with respect to treatment T0, as well as in the top soil layers in T2 and T3, but no changes were detected in the remainder of the layers in treatments T2 and T3. We can suggest that the waste studied can be used in the amelioration of saline and non-saline soils.