During the past 6 years, the General Biology Program at the Univ. of Minnesota has been exploring the use of computer-based multimedia to improve the quality of undergraduate instruction in large undergraduate courses. Our project has created an image library of about 3500 computer graphics, animations, and digital video sequences for lecture support, as well as the software to present and manage this image library. During the past 3 years, students have used computers for modeling, simulation, and problem-solving activities in the laboratory of our evolution and ecology undergraduate course. Most recently, we have begun to integrate the World Wide Web into our curriculum in a variety of ways. This presentation demonstrates the comprehensive way in which our Program has combined these “new” information technologies into our introductory courses. The general applicability of this approach to any discipline will be discussed.