Thirteen rootstocks grafted with Redhaven peach were established on a severe peach tree short-life (PTSL) site in central Georgia. Most rootstocks tested were peach seedling types: Lovell, Nemaguard, Guardian (BY520-9), BY520-8, Boone County, Bailey and two `Tennessee Natural' selections. A seedling plum rootstock, St. Julian, was also used. Clonal type rootstocks included a peach × almond hybrid, GF677; plum, GF43 and Damas 1869; and a plum hybrid, GF655-2. Trees on Guardian displayed the best survival with only 20% mortality due to PTSL, through 7 years. In contrast, 40% of trees on Lovell succumbed to PTSL. Currently, Lovell is the recommended rootstock for PTSL-prone sites. Other rootstocks ranged from 50% to 100% mortality due to PTSL. Trees on Guardian displayed significantly higher vigor through the first 4 years following planting compared to trees on Lovell. Furthermore, trees on Guardian produced significantly greater yields than those on Lovell, in all but 1 year. Rootstock effects on tree survival, vigor, bloom and harvest dates, fruit yield and size, and suckering will be discussed.