The effects of light intensity on three sweetpotato cultivars [Ipomoea batatas (L.) Lam] were evaluated in growth chambers, as part of NASA's Closed Ecological Life Support Systems (CELSS) program for long duration space missions. Vine cuttings of `TI-155', `GA Jet', and TUJ1 were grown using nutrient film technique (NFT) in a modified half Hoagland's solution with a 1:2.4 N:K ratio in channels (0.15×0.15×1.2 m). Plants were exposed to irradiance levels of 360 or 720 umols m-2s-1 with an 18/6 photoperiod in a randomized complete block design with two replications. Temperature was set at 28:22 lightdark and RH was 70%. Differences in plant response to were more related to cultivars than the effect of light intensity. Storage root number (8) fresh, (786 g/plant) and dry weights (139 g/plant) were highest for `TI-155' while foliage fresh and dry weights were highest for `TUJ1' when averaged across light levels. TI-155' (921 g/plant) and `GA Jet' (538 g/plant) produced greater yields at higher irradiance. `TUJ1' produced a higher yield (438 g/plant at the lower intensity compared to 219 (g/plant) at the higher intensity, suggesting this cultivar could produce storage roots in similar conditions in a CELSS.