Studies were conducted to evaluate container size and pretreatment on transplant survival and growth of guayule (Parthenium argentatum Gray). Seeds of cv. 11605 were planted in a greenhouse in two different container sizes. After 60 days half of the seedlings in both treatments were clipped, and then hand transplanted into the field. The height and width of 10 plants in each treatment were measured biweekly. The percent survival, date of flowering, seed germination and weight of 1000 seeds were determined. Plants produced in large containers had a higher survival rate, plant size and flowering rate. In addition non-clipped seedling had significantly higher survival rates. There were no significant differences in seed germination or in seed weights among treatments.