A closed, insulated, pallet production system (CIPPS) has been designed to meet current challenges: 1) Elimination of production related pollution. 2) Reduction and conservation of resources. 3) Improvement of working conditions. 4) Alternatives to pesticides. 5) Prevention of temperature extremes and rapid temperature fluctuations in the plant environment. Biological feasibility of CIPPS was established in research on pathogen epidemiology, water and fertilize efficiency, plant growth and development in CIPPS. Water and fertilizer ion movement-removal in the closed system was plant-driven in response to growth and transpiration; water and fertilizer use in CIPS was 10% of that applied to open containers. Growth of 28 plant species ranging from herbaceous annuals to woody perennials was greater in CIPPS than in control, individual containers. Phytophthora cinnamomi did not spread from inoculated to noninoculated plants within CIPPS. Inoculation with nonpathogenic bacteria increased plant growth (gfw) in CIPPS but not in open plant containers.