Jewel sweetpotato storage roots previously treated with ultraviolet (UV–C) light and then stored for 30 days before artificial inoculation with Fusarium solani showed increased resistance to Fusarium root rot; as indicated by reduced lesion size, the rate of decay development of rotted tissues. There was a hormetic relationship between the incidence of Fusarium root rot and UV–C doses. The optimum dose of UV which reduced Fusarium root rot was 3.6× 104 ergs/mm2. Exposure of sweetpotato to UV–C doses promoted phenylalanine ammonia–lyase (PAL)4 production with the maximum PAL activity occurring at 3.6×104 ergs/mm2. Crude extracts from UV–C treated sweetpotatoes reduced germination, germ tube elongation and growth of F. solani when compared to untreated extracts.