A field experiment was established in 1980 to determine the effect of different combined levels of ammonium nitrat e (196-695 kg/ha), potassium chloride (56-196 kg/ha) and magnesium oxide (123-437 kg/ha) on `Noble' and `Magnolia' muscadine cultivars (Vitis rotundifolia Mich.). NH4NO3 rates of 196 to 695 kg/ha did not produce significant differences in yields and pruning weights (P=0.05). 'Noble' produced similar yields at the highest and lowest N rates, with equivalent rates of K and Mg. KCl at 84 kg/ha and MgO at 123 kg/ha appeared to be adequate. Foliar levels of K, Mg and Zn were significantly different between treatments, but P, Ca and Fe were not (P=0.05). High levels of foliar K and Mg were associated with high treatment levels of K and Mg.